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KMID : 0604020170320020211
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Korean Journal of Critical Care Medicine
2017 Volume.32 No. 2 p.211 ~ p.217
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Extensive and Progressive Cerebral Infarction after Mycoplasma pneumoniae Infection
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Choi Yu-Hyeon
Jeong Hyung-Joo
Lee Bong-Jin
An Hong-Yul
Lee Eui-Jun
Park June-Dong
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Abstract
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Acute cerebral infarctions are rare in children, however they can occur as a complication of a Mycoplasma pneumoniae (MP) infection due to direct invasion, vasculitis, or a hypercoagulable state. We report on the case of a 5-year-old boy who had an extensive stroke in multiple cerebrovascular territories 10 days after the diagnosis of MP infection. Based on the suspicion that the cerebral infarction was associated with a macrolide-resistant MP infection, the patient was treated with levofloxacin, methyl-prednisolone, intravenous immunoglobulin, and enoxaparin. Despite this medical management, cerebral vascular narrowing progressed and a decompressive craniectomy became necessary for the patient’s survival. According to laboratory tests, brain magnetic resonance imaging, and clinical manifestations, the cerebral infarction in this case appeared to be due to the combined effects of hypercoagulability and cytokine-induced vascular inflammation.
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KEYWORD
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cerebral infarction, child, mycoplasma pneumoniae, thrombosis, vasculitis
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